Tremplin Award (2024)

Fonds de Recherche du Quebec Sante (FRQS) Doctoral Scholarship (2023)

BME Excellence Award (2023)

GREAT Travel Award (2021)

Centech Entrepreneurship Propulsion Prize (2019)

Dobson Practicum, Concordia University - Second Place (2019)

Surgical Innovation Competition, McGill University - Third Place (2019)

Forces AVENIR - First Place, Science and Technology (2018)

Peer-Reviewed Articles:

Paun, R.A., Dumut, D.C., Li, L., Radzioch, D., Tabrizian, M. Bacterial hitchhiking with drug-loaded nanoparticles as a drug delivery strategy for cancer immunotherapy. npj Biomed. Innov. 2, 3 (2025). https://doi.org/10.1038/s44385-024-00006-6

Van Der Sanden N., Paun R.A., Yitayew M., Boyadjian O., Tabrizian M. (2024) An Investigation of the Protein Corona in the Cellular Uptake of Nanoliposomes Under Flow Conditions Using Quartz Crystal Microbalance with Dissipation, Nanoscale Advances

Paun, RA, Jurchuk, S, Tabrizian, M. A landscape of recent advances in lipid nanoparticles and their translational potential for the treatment of solid tumors. Bioeng Transl Med. 2023;e10601. doi:10.1002/btm2.10601

Rasouli R, Paun RA, Tabrizian M. Sonoprinting nanoparticles on cellular spheroids via surface acoustic waves for enhanced nanotherapeutics delivery. Lab on a Chip. 2023;23(8):2091-105.

Centorame, A.; Dumut, DC.; Youssef, M.; Ondra, M.; Kianicka, I.; Shah, J.; Paun, RA.; Ozdian, T.; Hanrahan, JW.; Gusev, E.; Petrof, B.; Hajduch, M.; Pislariu, R.; De Sanctis, JB.; Radzioch, D. Treatment with LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated with CF Lung Disease. Frontiers in Pharmacology 2022, 13:876842, doi: 10.3389/fphar.2022.876842

Paun, R.A.; Dumut, D.C.; Centorame, A.; Thuraisingam, T.; Hajduch, M.; Mistrik, M.; Dzubak, P.; De Sanctis, J.B.; Radzioch, D.; Tabrizian, M. One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy. Pharmaceutics 2022, 14, 640. https://doi.org/10.3390/pharmaceutics14030640

“24-Hour ambulatory blood pressure monitoring 7 years after intensive care unit admission” Hessey, E., Paun, A., Benisty, K. et al. Pediatr Nephrol. 2022 Jan. https://doi.org/10.1007/s00467-021-05392-2

"Follow up after neonatal heart disease repair: Watch out for chronic kidney disease and hypertension!" Louis Huynh, Sara Rodriguez Lopez, et. al. Pediatr Nephrol. 2020 Nov;35(11):2137-2145.

"Paucity of renal follow-up by school age after neonatal cardiac surgery" Sara Rodriguez Lopez, Louis Huynh et. al. Cardiol Young. 2020 Jun;30(6):822-828.

Peer-Reviewed Abstracts:

Centorame A, Dumut C, Youssef M, Ondra M, Kianicka I, Shah J, Paun RA, Ozdian T, Hanrahan J, Gusev E, Petro B, Hajduch FM, Pislariu R, De Sanctis J, Radzioch D. (2022). 657 Combinatory treatment of LAU-7b with triple therapy results in improved lung physiology and restored fatty acid and lipid levels. North American Cystic Fibrosis Conference

Paun RA, Rasouli R, Dumut DC, Radzioch D, Tabrizian M. (2022). The bacterium Magnetospirillum gryphiswaldense improves the accumulation of surface-adsorbed nanoparticles into the core of 3D cancer models. 32nd conference of the European Society for Biomaterials (Bordeaux, FR).

Paun RA, Dumut DC, Thuraisingam T, Hajduch M, Dzubak P, De Sanctis J, Radzioch D, Tabrizian M. (2022). Synthesis and stabilization of nanoliposomal of copper diethyldithiocarbamate using poly (ethylene glycol)-carboxylate for cancer therapy. Presented at the Joint Symposium of the Society for Biomaterials and Japanese Society for Biomaterials

Raggi C, M’Callum M, Mangahas C, Selleri S, Pham T, Paun RA, Benabdallah B, Beauséjour C, Schwartz R, Haddad E, Paganelli M. (2018). Human stem cell-derived encapsulated liver tissue allows to safely treat acute liver failure in immunocompetent mice without immunosuppression. The Liver Meeting, American Association for the Study of Liver Diseases

Huynh L, Hessey E, Pizzi M, Paun RA, Palijan A, Joffe A, Garros D, Dancea A, Mackie A, Gottesman R, Zappitelli M, Morgan C. (2017). Evaluation of long-term renal outcomes in neonates after cardiac surgery. 49th Annual Canadian Society of Nephrology Conference

Hessey E, Palijan A, Pizzi M, Paun RA, Zappitelli M. (2016). Development of hypertension after acute kidney injury in the pediatric intensive care unit. American Society of Nephrology Kidney Week Conference 2016

Hessey E, Palijan A, Pizzi M, Paun RA, Zappitelli M. (2016). Long-term development of hypertension following acute kidney injury in the pediatric intensive care unit. 8th World Congress on Pediatric Intensive and Critical Care

Patents:

Perfusion Bioreactor, Perfusion Device, Artificial Liver System, and Related Methods. Filed in: CA, KR, EP, US, CN, AU. WO2019222847A1.

Conferences:

A. Mouncef, R. A. Paun, L. Li, M. Tabrizian, D. Radzioch. “Polymer-stabilized Liposomes for Enhanced Delivery of Cancer Immunotherapy Drug Combinations”, RI-MUHC Summer Student Research Day 2024, August 14, 2024, Montreal, Canada.

R. A. Paun, L. Li, D. C. Dumut, D. Radzioch, M. Tabrizian, “Delivering immunotherapy drug combinations using lipid-polymer nanoparticles for cancer therapy”, CRS2024, July 8-12, 2024, Bologna, Italy.

S. Jurchuk, R. A. Paun, M. Tabrizian. “Genetically engineered E. coli for the controlled release of anti-cancer toxins to solid tumors”, CRS2024, July 8-12, 2024, Bologna, Italy.

Paun, R.A., Dumut, D.C., Ling, L., Radzioch, D., Tabrizian, M. (2023). Co-delivery of 6-bromo-indirubin-3-oxime and copper diethyldithiocarbamate using nanoparticle hybrids for the treatment of refractory melanoma. The 17th International Summer Schools on Nanoscience and Nanotechnology, Organic Electronics, and Nanomedicine. Poster presentation. Thessaloniki, GR, 1-8 July 2023.

Dumut, D.C., Frydrych, I., Popper, M., Garic, D., Paun, R.A., Centorame, A., Canavan, O., Shah, J., Mistrik, M., Dzubak, P., Bartek, J., Hajduch, M., De Sanctis, J.B., Radzioch, D. (2023). Disulfiram metabolite modulates NK and T cell cytotoxicity against metastatic colorectal cancer through tumor derived NKG2D ligands. The American Association for Cancer Research Annual Meeting. Poster presentation. Orlando, USA, 14-19 April 2023.

Paun, R.A., Dumut, D.C., Radzioch, D., Tabrizian, M. (2023). Lipid-polymer hybrid nanoparticles encapsulating 6-bromo-indirubin-3-oxime and copper diethyldithiocarbamate for the treatment of refractory melanoma. 7th Biological and Biomedical Engineering Symposium. Oral presentation. Montréal, QC, May 2023.

Jurchuk, S., Paun, R.A., Tabrizian, M. (2023). Coating system for E. coli as a systemic drug delivery vehicle into solid tumors. 7th Biological and Biomedical Engineering Symposium. Poster presentation. Montréal, QC, May 2023.

Paun, R.A., Dumut, D.C., Radzioch, D., Tabrizian, M. (2023). Development of lipid-polymer hybrid nanoparticles for the co-encapsulation of 6-bromo-indirubin-3’-oxime and copper diethyldithiocarbamate for synergistic cancer therapy. Society for Biomaterials Annual Meeting and Exposition. Oral presentation. San Diego, USA 19-22 April 2023.

Centorame A, Dumut C, Youssef M, Ondra M, Kianicka I, Shah J, Paun RA, Ozdian T, Hanrahan J, Gusev E, Petro B, Hajduch FM, Pislariu R, De Sanctis J, Radzioch D. (2022). 657 Combinatory treatment of LAU-7b with triple therapy results in improved lung physiology and restored fatty acid and lipid levels. North American Cystic Fibrosis Conference

Paun RA, Rasouli R, Dumut DC, Radzioch D, Tabrizian M. (2022). The bacterium Magnetospirillum gryphiswaldense improves the accumulation of surface-adsorbed nanoparticles into the core of 3D cancer models. Presented at the 32nd conference of the European Society for Biomaterials (Bordeaux, FR).

Paun RA, Dumut DC, Thuraisingam T, Hajduch M, Dzubak P, De Sanctis J, Radzioch D, Tabrizian M. (2022). Synthesis and stabilization of nanoliposomal of copper diethyldithiocarbamate using poly (ethylene glycol)-carboxylate for cancer therapy. Presented at the Joint Symposium of the Society for Biomaterials and Japanese Society for Biomaterials (Honolulu, HI).

Paun RA, Dumut DC, Centorame A, Thuraisingam T, Hajduch M, Dzubak P, De Sanctis J, Tabrizian M, Radzioch D. (2021). The disulfiram derivative diethyldithiocarbamate-copper demonstrates anti-neoplastic activity against multiple melanoma phenotypes. 5th Infectious Disease and Immunity in Global Health Student Research Day. Research Institute of the McGill University Health Centre, Montreal, QC, Canada (poster presentation)

Centorame A, Ondra M, Dumut DC, Paun RA, Shah J, Liao J, Hanrahan JW, De Sanctis J,, Hajduch M, Radzioch D. (2021) Effectiveness of triple therapy correcting functional expression of mutated CFTR protein - HiBiT technology for CFTR monitoring. Infectious Disease and Immunity in Global Health Student Research Day. Research Institute of the McGill University Health Centre, Montreal, QC, Canada (poster presentation)

Invited Speaker:

BioConnect (2021)

Invited Lecturer:

McGill University BMDE/DENT 504 - Biomaterials and Bioperformance. (2023). Biological characterization of biomaterials: Part II (soft tissues)

Other research projects involved the physicochemical characterization and optimization of a PEG-based hydrogel for cell encapsulation, and the design and development of a perfusion bioreactor.

Student Intern - Technical Advisor at Norton Rose Fulbright Canada

Medical Editor for the McGill Journal of Medicine